Creatine Monohydrate vs Creatine HCL (Hydrochloride)

Creatine Monohydrate

• Composed of one molecule of creatine bound to one molecule of water. Less water-soluble due to the relatively large size of the molecule and its weak polar nature. The water molecule bound to the creatine stabilizes the structure but does not enhance solubility. 

Creatine HCL

• Creatine bound to a hydrochloride group (LHC), forming a salt. Highly-water soluble because the hydrochloride group increases the polarity of the molecule. The hydrochloride group lowers the pH of the solution it is dissolved in, making it more acidic and aiding its solubility in water. 

Creatine Monohydrate Pros

• Most common and researched form
• Very affordable

Creatine Monohydrate Cons

• Less soluble in water so can cause stomach issues

Creatine HCL Pros

• More water-soluble
• Can have better absorption
• Less problems with stomach discomfort

Creatine HCL Cons

• Less Researched
• Most expensive

Choose Creatine Monohydrate if you are looking for a cost-effective, well researched option that works for most people

Choose Creatine HCL if you have trouble with bloating, stomach discomfort, or prefer a form with faster absorption.