What is Creatine Ethyl Ester , and how does it work so well?

Regular creatine monohydrate has been shown effective at increasing lean muscle mass1,2,3,4, muscle strength5,6 and athletic performance.7,8

However, regular creatine monohydrate is absorbed poorly by the body - and its effectiveness is dependant upon the cells ability to absorb it. The poor absorption rate of regular creatine monohydrate requires the creatine user to ingest large dosages of creatine to achieve desired effect.

Because creatine draws water to the cell, and because most ingested creatine monohydrate is not absorbed, unabsorbed creatine will sit outside of the target cell with the water, and this will result in the "creatine bloat."

Long-term clinical studies have proven that creatine monohydrate is safe for use by persons free of medical complication9, but why would you want to ingest more creatine monohydrate than you have to simply because your creatine is inefficient?

Creatine ethyl ester is creatine monohydrate with an ester attached. The attachment of an ester is significant, because esters are found in the fat tissue of animals. But, why is this important? What role does this have in the absorption of creatine?

All substances that you put into your body will affect its operation. There are three ways that substances can affect a cells operation. They are:

• Ligand binding to protein receptor sites.
• Secondary messenger / metabotropic systems
• Passive permeation of the cell wall via lipids

When a substance enters the body and affects the bodies operation, it is known as a ligand. The soma and dendrites of the cell have protein receptor sites to which ligands can bind. The process of a ligand binding with a receptor site is akin to a lock and key: only keys of a certain shape work with certain locks. When they work and cause the cells stimulation they are called agonists. When they block the cell from functioning they are called antagonists.

When a ligand binds with the receptor site of a target cell, the cell, in the simplest of cases, changes its shape, opens up its ion channels and changes its function. In so-called "secondary messenger" or metabotropic cells, the ligand binds with the receptor site and an internal protein known as a g-protein is released. This released protein then binds to an internal site inside of the cell, and then the cell changes its behavior by opening its ion channels. Cells that operate in this way are known as metabotropic cells because their operation requires metabolic energy.

Passive permeation is a process that describes the diffusion of a substance across a cell membrane through the use of lipids as transport mechanisms. Because no "work" is being done by the cell in this model, this model is called passive permeation.

Creatine monohydrate utilizes lipids to permeate the cell wall and enter the cell. Because of this, the esterficiation of creatine, and the presence of esters in animal fat tissue, becomes significant.

Creatine monohydrate is semi-lipopholic. This means that it inefficiently uses fat as a transport mechanism. The esterficiation of substances will increase their lipopholic abilities, and thus esterified creatine will use fat more efficiently to permeate the cell wall and exert its effects upon cellular function than its unesterified creatine monohydrate counterpart

This means, simply, that not only will dosage requirements be lower, but the absorption of esterified creatine will be increased and the infamous "creatine bloat" will be eliminated!

With most other CEE caps you are only getting 1.5-2g of CEE per serving however; CEE 3000 gets you a whopping 3g of pure CEE in each serving all for only $23.95... That's only $0.39 per serving!

You'll pay over $0.80 per serving for CEE Pro by MuscleTech and it only has 2.1g of CEE or CEX from VPX is only 2.4g and you'll pay $0.43 per serving for that! Save big and get the CEE that you need in the dosage that will actually make a difference you can see... order CEE 3000 by NRG-X Labs today!

Supplement Facts:
Serving Size: 4 Capsules
Servings Per Container: 60

• Creatine Ethyl Ester HCl 3000mg
• Other Ingredients: Magnesium stearate, gelatin.

Suggested Use: As a dietary supplement, take 4 capsules twice daily.